In extreme environments such as core-collapse supernovae, neutron-star mergers, and the early Universe, neutrinos are dense enough that their self-interactions significantly affect, if not dominate, their flavor dynamics. In order to develop techniques for characterizing the resulting quantum entanglement, I present the results of simulations of Dirac neutrino-neutrino interactions that include all three physical neutrino flavors and were performed on D-Wave Inc.’s Advantage 5000+ qubit annealer. These results are checked against those from exact classical simulations, which are also used to compare the Dirac neutrino-neutrino interactions to neutrino-antineutrino and Majorana neutrino-neutrino interactions. The D-Wave Advantage annealer is shown to be able to reproduce time evolution with the precision of a classical machine for small numbers of neutrinos and to do so without Trotter errors. However, it suffers from poor scaling in qubit-count with the number of neutrinos. Two approaches to improving the qubit-scaling are discussed, but only one of the two shows promise.